2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. P2X Receptor
  5. P2X Receptor Activator

P2X Receptor Activator

P2X Receptor Isoform Comparison

P2X Receptor Activator (1):

Cat. No. Product Name Effect Purity
  • HY-164426
    HEI3090
    		Activator 99.04%
    HEI3090 is a P2X7R activator. HEI3090 stimulates dendritic cells expressing P2X7R to produce IL-18, which subsequently promotes Natural Killer cells and CD4 T cells within tumors to produce IFN-γ, leading to a sustained antitumor response. HEI3090 can be used to enhance the efficacy of αPD-1 therapy in non-small cell lung cancer (NSCLC).